Panama City to Spain flight information

• The most popular flight routes from Panama City to Spain are Panama City to Barcelona, Panama City to Madrid, Panama City to Malaga
• The cheapest flight from Panama City to Spain is from Panama City to Madrid, with airfares starting at XAF 395629
• The fastest flight from Panama City to Spain is from Panama City to Madrid, with an average flight time of 9h 35m
• The most popular city destinations in Spain are Barcelona, Madrid, Palma de Mallorca