Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline United Airlines

The cheapest airline(s) flying from Des Moines to Chicago is United Airlines.

  • United Airlines United Airlines
  • American Airlines American Airlines
Cheapest Month December

Travel Period: December 2024 - November 2025

The cheapest month(s) to fly from Des Moines to Chicago is December.

  • Dec 2024
  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
Cheapest Day of the Week Friday

The cheapest day(s) of the week to fly from Des Moines to Chicago is Friday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Sat, 2 Nov, 2024

  • Time Earliest
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  • Stopover
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    • Airline Filter by Airline
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      • Availability
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      • 18:54 DSM
        20:25 ORD
        1Hrs, 31m Direct
      • DSMDes Moines Airport 18:54 - ORD 20:25 1h 31m Direct
      • DSMDes Moines Airport 18:54
      • ORDChicago O'Hare International Airport 20:25
      • 1h 31m
      • Direct
      • United Airlines (UA 5599)Embraer 175
      • United Airlines (UA 5599)
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      • Embraer 175
      • 18:54 DSM
        20:22 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 18:54 - ORD 20:22 1h 28m Direct
      • DSMDes Moines Airport 18:54
      • ORDChicago O'Hare International Airport 20:22
      • 1h 28m
      • Direct
      • United Airlines (UA 1807)Boeing 737 700
      • United Airlines (UA 1807)
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      • Boeing 737 700
      • 18:54 DSM
        20:22 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 18:54 - ORD 20:22 1h 28m Direct
      • DSMDes Moines Airport 18:54
      • ORDChicago O'Hare International Airport 20:22
      • 1h 28m
      • Direct
      • United Airlines (UA 1807)Airbus
      • United Airlines (UA 1807)
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      • Airbus
      • 21:34 DSM
        23:02 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 21:34 - ORD 23:02 1h 28m Direct
      • DSMDes Moines Airport 21:34
      • ORDChicago O'Hare International Airport 23:02
      • 1h 28m
      • Direct
      • United Airlines (UA 2223)Airbus
      • United Airlines (UA 2223)
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      • Airbus
      • 21:34 DSM
        23:02 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 21:34 - ORD 23:02 1h 28m Direct
      • DSMDes Moines Airport 21:34
      • ORDChicago O'Hare International Airport 23:02
      • 1h 28m
      • Direct
      • United Airlines (UA 2223)Airbus
      • United Airlines (UA 2223)
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        • -
      • Airbus
      • 05:20 DSM
        06:52 ORD
        1Hrs, 32m Direct
      • DSMDes Moines Airport 05:20 - ORD 06:52 1h 32m Direct
      • DSMDes Moines Airport 05:20
      • ORDChicago O'Hare International Airport 06:52
      • 1h 32m
      • Direct
      • American Airlines (AA 6389)Crj 700 Canadair Regional
      • American Airlines (AA 6389)
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        • S
      • Crj 700 Canadair Regional
      • 08:00 DSM
        09:27 ORD
        1Hrs, 27m Direct
      • DSMDes Moines Airport 08:00 - ORD 09:27 1h 27m Direct
      • DSMDes Moines Airport 08:00
      • ORDChicago O'Hare International Airport 09:27
      • 1h 27m
      • Direct
      • United Airlines (UA 1363)Boeing 737 800
      • United Airlines (UA 1363)
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        • S
      • Boeing 737 800
      • 11:00 DSM
        12:32 ORD
        1Hrs, 32m Direct
      • DSMDes Moines Airport 11:00 - ORD 12:32 1h 32m Direct
      • DSMDes Moines Airport 11:00
      • ORDChicago O'Hare International Airport 12:32
      • 1h 32m
      • Direct
      • American Airlines (AA 6389)Crj 700 Canadair Regional
      • American Airlines (AA 6389)
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      • Crj 700 Canadair Regional
      • 11:25 DSM
        12:56 ORD
        1Hrs, 31m Direct
      • DSMDes Moines Airport 11:25 - ORD 12:56 1h 31m Direct
      • DSMDes Moines Airport 11:25
      • ORDChicago O'Hare International Airport 12:56
      • 1h 31m
      • Direct
      • United Airlines (UA 3597)Embraer 175
      • United Airlines (UA 3597)
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      • Embraer 175
      • 11:25 DSM
        12:56 ORD
        1Hrs, 31m Direct
      • DSMDes Moines Airport 11:25 - ORD 12:56 1h 31m Direct
      • DSMDes Moines Airport 11:25
      • ORDChicago O'Hare International Airport 12:56
      • 1h 31m
      • Direct
      • United Airlines (UA 3597)Embraer 170
      • United Airlines (UA 3597)
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      • Embraer 170
      • 11:25 DSM
        12:53 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 11:25 - ORD 12:53 1h 28m Direct
      • DSMDes Moines Airport 11:25
      • ORDChicago O'Hare International Airport 12:53
      • 1h 28m
      • Direct
      • United Airlines (UA 2306)Airbus
      • United Airlines (UA 2306)
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      • 11:25 DSM
        12:53 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 11:25 - ORD 12:53 1h 28m Direct
      • DSMDes Moines Airport 11:25
      • ORDChicago O'Hare International Airport 12:53
      • 1h 28m
      • Direct
      • United Airlines (UA 2306)Airbus
      • United Airlines (UA 2306)
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      • 11:41 DSM
        13:15 ORD
        1Hrs, 34m Direct
      • DSMDes Moines Airport 11:41 - ORD 13:15 1h 34m Direct
      • DSMDes Moines Airport 11:41
      • ORDChicago O'Hare International Airport 13:15
      • 1h 34m
      • Direct
      • American Airlines (AA 6084)Crj Canadair Regional
      • American Airlines (AA 6084)
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      • Crj Canadair Regional
      • 15:20 DSM
        16:48 ORD
        1Hrs, 28m Direct
      • DSMDes Moines Airport 15:20 - ORD 16:48 1h 28m Direct
      • DSMDes Moines Airport 15:20
      • ORDChicago O'Hare International Airport 16:48
      • 1h 28m
      • Direct
      • United Airlines (UA 1568)Airbus
      • United Airlines (UA 1568)
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      • Airbus
      • 16:00 DSM
        17:34 ORD
        1Hrs, 34m Direct
      • DSMDes Moines Airport 16:00 - ORD 17:34 1h 34m Direct
      • DSMDes Moines Airport 16:00
      • ORDChicago O'Hare International Airport 17:34
      • 1h 34m
      • Direct
      • American Airlines (AA 6047)Crj Canadair Regional
      • American Airlines (AA 6047)
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      • Crj Canadair Regional
      • 17:00 DSM
        18:34 ORD
        1Hrs, 34m Direct
      • DSMDes Moines Airport 17:00 - ORD 18:34 1h 34m Direct
      • DSMDes Moines Airport 17:00
      • ORDChicago O'Hare International Airport 18:34
      • 1h 34m
      • Direct
      • American Airlines (AA 6047)Crj Canadair Regional
      • American Airlines (AA 6047)
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      • Crj Canadair Regional
      • 17:09 DSM
        18:43 ORD
        1Hrs, 34m Direct
      • DSMDes Moines Airport 17:09 - ORD 18:43 1h 34m Direct
      • DSMDes Moines Airport 17:09
      • ORDChicago O'Hare International Airport 18:43
      • 1h 34m
      • Direct
      • American Airlines (AA 6047)Crj Canadair Regional
      • American Airlines (AA 6047)
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      • 18:25 DSM
        23:05 MDW
        4Hrs, 40m 1 Stop (STL)
      • DSMDes Moines Airport 18:25 - MDW 23:05 4h 40m 1 Stop (STL) Saint Louis
      • DSMDes Moines Airport 18:25
        STLSt Louis Lambert Intl Airport 21:55
      • STLSt Louis Lambert Intl Airport 19:30
        MDWChicago Midway Airport 23:05
      • 4h 40m (2h 25m)
      • 1 Stop STL · Saint Louis 2h 25m
      • Southwest Airlines (WN 2925)Boeing 737 700
        Southwest Airlines (WN 652)Boeing 737 800
      • Southwest Airlines (WN 2925)
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      • 18:45 DSM
        23:05 MDW
        4Hrs, 20m 1 Stop (STL)
      • DSMDes Moines Airport 18:45 - MDW 23:05 4h 20m 1 Stop (STL) Saint Louis
      • DSMDes Moines Airport 18:45
        STLSt Louis Lambert Intl Airport 21:55
      • STLSt Louis Lambert Intl Airport 19:50
        MDWChicago Midway Airport 23:05
      • 4h 20m (2h 05m)
      • 1 Stop STL · Saint Louis 2h 05m
      • Southwest Airlines (WN 372)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 2364)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 372)
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      • 05:30 DSM
        09:25 MDW
        3Hrs, 55m 1 Stop (STL)
      • DSMDes Moines Airport 05:30 - MDW 09:25 3h 55m 1 Stop (STL) Saint Louis
      • DSMDes Moines Airport 05:30
        STLSt Louis Lambert Intl Airport 08:15
      • STLSt Louis Lambert Intl Airport 06:50
        MDWChicago Midway Airport 09:25
      • 3h 55m (1h 25m)
      • 1 Stop STL · Saint Louis 1h 25m
      • Southwest Airlines (WN 372)Boeing 737 700
        Southwest Airlines (WN 498)Boeing 737 700
      • Southwest Airlines (WN 372)
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      • 06:50 DSM
        11:50 MDW
        5Hrs, 00m 1 Stop (STL)
      • DSMDes Moines Airport 06:50 - MDW 11:50 5h 1 Stop (STL) Saint Louis
      • DSMDes Moines Airport 06:50
        STLSt Louis Lambert Intl Airport 10:40
      • STLSt Louis Lambert Intl Airport 08:05
        MDWChicago Midway Airport 11:50
      • 5h (2h 35m)
      • 1 Stop STL · Saint Louis 2h 35m
      • Southwest Airlines (WN 372)Boeing 737 700
        Southwest Airlines (WN 2364)Boeing 737 800
      • Southwest Airlines (WN 372)
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      • 16:10 DSM
        20:05 MDW
        3Hrs, 55m 1 Stop (STL)
      • DSMDes Moines Airport 16:10 - MDW 20:05 3h 55m 1 Stop (STL) Saint Louis
      • DSMDes Moines Airport 16:10
        STLSt Louis Lambert Intl Airport 18:55
      • STLSt Louis Lambert Intl Airport 17:15
        MDWChicago Midway Airport 20:05
      • 3h 55m (1h 40m)
      • 1 Stop STL · Saint Louis 1h 40m
      • Southwest Airlines (WN 2925)Boeing 737 800
        Southwest Airlines (WN 1253)Boeing 737 700
      • Southwest Airlines (WN 2925)
        • -
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        • -
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        • F
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      No Schedules Sorry, there are no schedules matching your filters. Try removing one. reset
      What’s the fastest flight time from Des Moines to Chicago?

      The fastest flight time for direct flights from Des Moines to Chicago is 1 hour 27 minutes. Check latest flight schedules & prices on Wego.

      How far is Chicago from Des Moines?

      The flight distance between Des Moines and Chicago is 497km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 05:20. The last flight of the day departs at 18:25. See the full list of flight times on Wego.

      How many airlines offer direct flights from Des Moines to Chicago?

      There are 2 airlines that offer direct flights from Des Moines to Chicago. Find out the list of airlines on Wego.

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      Des Moines Airport DSM

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